新生物技术/Bcl-2（凋亡和滤泡性淋巴瘤标记物）/596-MSM11-P1
商品编号：
596-MSM11-P1
品牌：
NeoBio
市场价：
¥8580.00
美元价：
5148.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product Details
Synonyms
Apoptosis regulator Bcl-2, B-cell CLL/lymphoma-2
Positive Control
Jurkat, K562, HL-60 or HeLa cells. Tonsil or follicular lymphomas.
Known Applications & Suggested Dilutions
Flow Cyt, IF, Western Blot, IHC-P More Details
Flow Cytometry (1-2ug/million cells)Immunofluorescence (1-2ug/ml)Western Blot (1-2ug/ml)Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10mM Tris with 1mM EDTA Buffer, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Immunogen
Recombinant full-length human BCL2 protein
Cellular Localization
Outer mitochondrial membranes and endoplasmic reticulum as well as nuclear membranes.
Species Reactivity
Human.
Host / Ig Isotype
Mouse / IgG1, kappa
Mol. Weight of Antigen
25-26kDa
品牌介绍
NeoBio的SFN（stratifin）是一种p53诱导的肿瘤抑制基因，其响应DNA损伤而被激活，通过阻止cdc2-cyclin B1复合物进入细胞核而导致细胞周期停滞在G2期。在乳腺癌，肺癌，前列腺癌，肝癌和胃癌中被灭活。当在上皮性卵巢癌中观察到其下调时，其与不良预后相关。SFN表达可能有助于癌细胞增殖以及人类胃肠道癌的发展和/或进展。
品牌分类
抗体
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