新生物技术/ALK(间变性淋巴瘤激酶)/CD246/238-RBM6-P1ABX
商品编号:
238-RBM6-P1ABX
品牌:
NeoBio
市场价:
¥8580.00
美元价:
5148.00
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
ProductDetails
Synonyms
Alpha-methylacyl-CoARacemase,CBAS4,Da1-8,Macr1,RACE,RM
PositiveControl
HEKcells.ProstateAdenocarcinoma.
KnownApplications&SuggestedDilutions
WesternBlot,IHC-PMoreDetails
WesternBlot(1-2ug/ml)Immunohistochemistry(Formalin-fixed)(1-2ug/mlfor30minutesatRT)(Stainingofformalin-fixedtissuesrequiresheatingtissuesectionsin10mMTriswith1mMEDTA,pH9.0,for45minat95°CfollowedbycoolingatRTfor20minutes)Optimaldilutionforaspecificapplicationshouldbedetermined.
Immunogen
RecombinanthumanAMACRproteinfragment(aroundaa297-394)(exactsequenceisproprietary)
CellularLocalization
Cytoplasmic(granular)
SpeciesReactivity
Human.
Host/IgIsotype
Rabbit/IgG
Mol.WeightofAntigen
42kDa
品牌介绍
NeoBio的SFN(stratifin)是一种p53诱导的肿瘤抑制基因,其响应DNA损伤而被激活,通过阻止cdc2-cyclin B1复合物进入细胞核而导致细胞周期停滞在G2期。在乳腺癌,肺癌,前列腺癌,肝癌和胃癌中被灭活。当在上皮性卵巢癌中观察到其下调时,其与不良预后相关。SFN表达可能有助于癌细胞增殖以及人类胃肠道癌的发展和/或进展。
品牌分类
抗体
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