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当前位置: 首页 > 产品中心 > Electrophysiological > NeoBiotechnologies/14-3-3E / Tryptophan 5-Monooxygenase/7531-MSM1-P1ABX
商品详细NeoBiotechnologies/14-3-3E / Tryptophan 5-Monooxygenase/7531-MSM1-P1ABX
NeoBiotechnologies/14-3-3E / Tryptophan 5-Monooxygenase/7531-MSM1-P1ABX
NeoBiotechnologies/14-3-3E / Tryptophan 5-Monooxygenase/7531-MSM1-P1ABX
商品编号: 7531-MSM1-P1ABX
品牌: NeoBio
市场价: ¥8580.00
美元价: 5148.00
产地: 美国(厂家直采)
公司:
产品分类: 电生理设备
公司分类: Electrophysiological
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

ProductDetails

Synonyms

MDS;epididymisluminalprotein2;mitochondrialimportstimulationfactor(MSF)Lsubunit;MitochondrialimportstimulationfactorLsubunit;MSFL;proteinkinaseCinhibitorprotein-1

PositiveControl

HEK-293orA-431celllines.

KnownApplications&SuggestedDilutions

WesternBlot,IHC-PMoreDetails

WesternBlot(1-2ug/ml)Immunohistochemistry(Formalin-fixed)(1-2ug/mlfor30minatRT),(Stainingofformalin-fixedtissuesrequiresheatingtissuesectionsin10mMTriswith1mMEDTA,pH9.0,for45minat95°CfollowedbycoolingatRTfor20minutes)Optimaldilutionforaspecificapplicationshouldbedetermined.

Immunogen

Recombinanthumanfull-lengthYWHAEprotein

CellularLocalization

Cytoplasm.Melanosome.

SpeciesReactivity

Human.

Host/IgIsotype

Mouse/IgG2a,kappa

Mol.WeightofAntigen

29.4kDa
品牌介绍
NeoBio的SFN(stratifin)是一种p53诱导的肿瘤抑制基因,其响应DNA损伤而被激活,通过阻止cdc2-cyclin B1复合物进入细胞核而导致细胞周期停滞在G2期。在乳腺癌,肺癌,前列腺癌,肝癌和胃癌中被灭活。当在上皮性卵巢癌中观察到其下调时,其与不良预后相关。SFN表达可能有助于癌细胞增殖以及人类胃肠道癌的发展和/或进展。